EOC317 (ACTB-1003)
目录号: A14431
FGFR1 inhibitor
ACTB-1003 是一种口服激酶抑制剂,针对癌症突变(FGFR抑制)、血管生成(VEGFR2和Tie-2抑制)并诱导凋亡(针对位于PI3激酶下游的RSK和p70S6K)。
Discription | ACTB-1003 is an oral kinase inhibitor targeting cancer mutations (FGFR inhibition), angiogenesis (inhibition of VEGFR2 and Tie-2) and induces apoptosis (targeting RSK and p70S6K, downstream of PI3 kinase). |
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Targets |
目录号 | A14431 |
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分子式 | C27H26F5N7O3 |
分子量 | 591.53 |
CAS号 | 939805-30-8 |
SMILES | COCC1=C(N2C(=C1C3=CC(=C(C=C3)NC(=O)NC4=C(C=CC(=C4)C(F)(F)F)F)F)C(=NC=N2)N)CN5CCOCC5 |
其他名称 | ACTB1003, ACTB 1003 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |