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Adapalene是一类RAR和RXR双重的激动剂，主要用于治疗痤疮。
靶点信息
| RARγ | RARβ | RXR | ||
| In vitro | DMSO | 7 mg/mL (16.97 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.24 mL | 121.21 mL | 242.42 mL |
| 0.5 mM | 4.85 mL | 24.24 mL | 48.48 mL |
| 1 mM | 2.42 mL | 12.12 mL | 24.24 mL |
| 5 mM | 0.48 mL | 2.42 mL | 4.85 mL |
*The above data is based on the productmolecular weight 412.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A10038 |
|---|---|
| M. Wt | 412.5 |
| Formula | C28H28O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 106685-40-9 |
| Synonyms | Differin |
| SMILES | COC1=C(C=C(C=C1)C2=CC3=C(C=C2)C=C(C=C3)C(=O)O)C45CC6CC(C4)CC(C6)C5 |
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