Adavivint

Name: Adavivint
SKU: A19257
Price: 245 CNY
Rating: 5 (288 reviews)

目录号: A19257

Wnt 抑制剂

Adavivint（SM04690；Lorecivivint）是一种强效且选择性的canonical Wnt signaling抑制剂，在SW480结肠癌细胞中通过高通量TCF/LEF-reporter检测，其EC50为19.5 nM。

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Grouped product items
规格	价格	库存
1mg	¥245.00	现货
5mg	¥560.00	现货
10mg	¥840.00	现货
25mg	¥1,400.00	现货
50mg	¥2,520.00	现货
100mg	¥3,780.00	现货
*10mM 1mL in DMSO**	¥630.00	现货
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Data Sheet

SDS

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生物活性

Discription

Adavivint (SM04690; Lorecivivint) is a potent and selective inhibitor of canonical Wnt signaling, with an EC50 of 19.5 nM via a high-throughput TCF/LEF-reporter assay in SW480 colon cancer cells.

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A19257
分子式	C29H24FN7O
分子量	505.55
CAS号	1467093-03-3
SMILES	CC(C)CC(NC1=CC(C2=CC3=C(NN=C3C(N4)=NC5=C4C(C6=CC=CC(F)=C6)=CN=C5)C=C2)=CN=C1)=O
其他名称	SM04690, SM 04690, SM-04690; Lorecivivint
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	30 mg/mL (59.34 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.78 mL	98.9 mL	197.8 mL
0.5 mM	3.96 mL	19.78 mL	39.56 mL
1 mM	1.98 mL	9.89 mL	19.78 mL
5 mM	0.4 mL	1.98 mL	3.96 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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