Doxorubicin hydrochloride (Adriamycin)

Name: Doxorubicin hydrochloride (Adriamycin)
SKU: A10041
Price: 175 CNY
Rating: 5 (1 reviews)

目录号: A10041

topoisomerase II 抑制剂

1 篇发表文献

Adriamycin 是一种蒽环类抗生素，它通过插入 DNA 来发挥作用，而最严重的副作用是可能危及生命的心脏损伤。它常用于治疗多种癌症，包括血液恶性肿瘤、多种类型的癌症和软组织肉瘤。

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Grouped product items
规格	价格	库存
25mg	¥175.00	现货
50mg	¥280.00	现货
100mg	¥420.00	现货
200mg	¥630.00	现货
500mg	¥1,260.00	现货
1g	¥1,890.00	现货
*10mM 1mL in DMSO**	¥315.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用 Doxorubicin hydrochloride (Adriamycin)发表的1篇文献

Sanaz Naghibi, .et al. , Biosensors (Basel), 2022, May 29;12(6):373 PMID: 35735521

生物活性

Discription

Adriamycin is an anthracycline antibiotic, it works by intercalating DNA, while most serious adverse effect being life-threatening heart damage. It is commonly used in the treatment of a wide range of cancers, including hematological malignancies, many types of carcinoma, and soft tissue sarcomas.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10041
分子式	C27H29NO11.HCl
分子量	580
CAS号	25316-40-9
SMILES	C[C@H]1[C@H]([C@H](C[C@@H](O1)O[C@H]2C[C@@](CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O.Cl
其他名称	Doxorubicin
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	Warmed: 88 mg/mL (151.72 mM)
	Water	18 mg/mL (31.03 mM)
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.24 mL	86.21 mL	172.41 mL
0.5 mM	3.45 mL	17.24 mL	34.48 mL
1 mM	1.72 mL	8.62 mL	17.24 mL
5 mM	0.34 mL	1.72 mL	3.45 mL

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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