ADX-47273
目录号: A11181
mGluR5 modulator
ADX-47273 是一种用于科学研究的药物，它作为一种正向异构调节剂，选择性地作用于代谢型谷氨酸受体亚型 mGluR5。
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生物活性
| Discription | ADX-47273 is a drug used in scientific research which acts as a positive allosteric modulator selective for the metabotropic glutamate receptor subtype mGluR5. |
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| Cell Research |
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产品信息
| 目录号 | A11181 |
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| 分子式 | C20H17F2N3O2 |
| 分子量 | 369.36 |
| CAS号 | 851881-60-2 |
| SMILES | C1C[C@@H](CN(C1)C(=O)C2=CC=C(C=C2)F)C3=NC(=NO3)C4=CC=C(C=C4)F |
| 其他名称 | ADX47273 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 73 mg/mL (197.63 mM) | |
| Water | Insoluble | ||
| Ethanol | 29 mg/mL (78.51 mM) | ||
| In vivo | 30% propylene glycol, 5% Tween 80, 65% D5W | 28 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 27.07 mL | 135.37 mL | 270.74 mL |
| 0.5 mM | 5.41 mL | 27.07 mL | 54.15 mL |
| 1 mM | 2.71 mL | 13.54 mL | 27.07 mL |
| 5 mM | 0.54 mL | 2.71 mL | 5.41 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 851881-60-2 | 851881-60-2 供应商 | 851881-60-2 花费 | 851881-60-2 生产商 | 订购 851881-60-2 | 851881-60-2 代理商