Signaling Pathway
| Discription | Afloqualone, also known as HQ-495, is a centrally acting muscle relaxant. Afloqualone inhibits vestibular nystagmus probably due to both inhibition of selective polysynaptic transmission and enhancement of the effects of GABA and glycine in the lateral vestibular nucleus (LVN), and its GABA-enhancing effect is thought to be attributable to the increased sensitivity of GABA receptors of the LVN neuron site. |
|---|
| 目录号 | A17276 |
|---|---|
| 分子式 | C16H14FN3O |
| 分子量 | 283.3064 |
| CAS号 | 56287-74-2 |
| SMILES | O=C1N(C2=CC=CC=C2C)C(CF)=NC3=C1C=C(N)C=C3 |
| 其他名称 | HQ-495; HQ495; HQ 495. Afloqualone |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 53 mg/mL (187.08 mM) | |
| Water | Insoluble | ||
| Ethanol | 27 mg/mL (95.3 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 35.3 mL | 176.49 mL | 352.97 mL |
| 0.5 mM | 7.06 mL | 35.3 mL | 70.59 mL |
| 1 mM | 3.53 mL | 17.65 mL | 35.3 mL |
| 5 mM | 0.71 mL | 3.53 mL | 7.06 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
