AG-120 (Ivosidenib) racemic
目录号: A14386
IDH1 inhibitor
AG-120 是一种口服可用的异柠檬酸脱氢酶1型(IDH1)抑制剂,具有潜在的抗肿瘤活性。
Discription | AG-120 is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1), with potential antineoplastic activity. |
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目录号 | A14386 |
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分子式 | C28H22ClF3N6O3 |
分子量 | 582.97 |
CAS号 | 1448346-63-1 |
SMILES | C1CC(=O)N(C1C(=O)N(C2=CC(=CN=C2)F)C(C3=CC=CC=C3Cl)C(=O)NC4CC(C4)(F)F)C5=NC=CC(=C5)C#N |
其他名称 | AG120, AG 120, Ivosidenib |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 95 mg/mL (162.95 mM) | |
Water | Insoluble | ||
Ethanol | 95 mg/mL (162.95 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 17.15 mL | 85.77 mL | 171.54 mL |
0.5 mM | 3.43 mL | 17.15 mL | 34.31 mL |
1 mM | 1.72 mL | 8.58 mL | 17.15 mL |
5 mM | 0.34 mL | 1.72 mL | 3.43 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2