AG-1478 (Tyrphostin AG-1478)

Name: AG-1478 (Tyrphostin AG-1478)
SKU: A11022
Price: 245 CNY
Rating: 5 (2 reviews)

目录号: A11022

EGFR 抑制剂

2 篇发表文献

AG-1478（Tyrphostin AG-1478）是一种EGFR激酶抑制剂，其IC50值为3 nM。

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Grouped product items
规格	价格	库存
5mg	¥245.00	现货
10mg	¥385.00	现货
25mg	¥735.00	现货
50mg	¥1,400.00	现货
100mg	¥1,960.00	现货
200mg	¥2,555.00	现货
*10mM 1mL in DMSO**	¥315.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用AG-1478 (Tyrphostin AG-1478) 发表的2篇文献

Khattab M, .et al. , J Phys Chem B, 2018, May 3;122(17):4667-4679 PMID: 29629773

Muhammad Khattab, .et al. , Sci Rep, 2017, 7: 16271 PMID: 29176733

生物活性

Discription

AG-1478 (Tyrphostin AG-1478) is an inhibitor of EGFR kinase with an IC50 value of 3 nM.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A11022
分子式	C16H14ClN3O2
分子量	315.8
CAS号	153436-53-4
SMILES	COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Cl)OC
其他名称	AG1478, AG 1478
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	25 mg/mL (79.17 mM)
	Water	Insoluble
	Ethanol	13 mg/mL (41.17 mM)
In vivo	15% Captisol	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	31.67 mL	158.33 mL	316.66 mL
0.5 mM	6.33 mL	31.67 mL	63.33 mL
1 mM	3.17 mL	15.83 mL	31.67 mL
5 mM	0.63 mL	3.17 mL	6.33 mL

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