AG-17
目录号: A11949
EGFR 抑制剂
AG-17 是一种 EGF 受体激酶抑制剂，在人类表皮癌细胞系 A431 中的 IC50 值为 460 μM。
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生物活性
| Discription | AG-17 is an inhibitor of EGF receptor kinase with an IC50 value of 460 μM in the human epidermoid carcinoma cell line A431. | |||||
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产品信息
| 目录号 | A11949 |
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| 分子式 | C18H22N2O |
| 分子量 | 282.4 |
| CAS号 | 10537-47-0 |
| SMILES | CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)C=C(C#N)C#N |
| 其他名称 | NSC 242557, RG-50872, GCP 5126, SF 6847, Tyrphostin AG-17, Malonoben, Tyrphostin 9 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 51 mg/mL (180.6 mM) | |
| Water | Insoluble | ||
| Ethanol | 51 mg/mL (180.6 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 35.41 mL | 177.05 mL | 354.11 mL |
| 0.5 mM | 7.08 mL | 35.41 mL | 70.82 mL |
| 1 mM | 3.54 mL | 17.71 mL | 35.41 mL |
| 5 mM | 0.71 mL | 3.54 mL | 7.08 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 10537-47-0 | 10537-47-0 供应商 | 10537-47-0 花费 | 10537-47-0 生产商 | 订购 10537-47-0 | 10537-47-0 代理商