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AG14361

目录号: A10046

PARP1 抑制剂

AG14361 是一种强效的 PARP 抑制剂,在 MMR(错配修复) -完好/缺陷细胞中增强了 TMZ 的细胞毒性。
Grouped product items
规格 价格 库存 数量
1mg
¥280.00
现货
2mg
¥420.00
现货
5mg
¥665.00
现货
10mg
¥1,155.00
现货
25mg
¥2,240.00
现货
50mg
¥3,815.00
现货
100mg
¥6,265.00
现货
10mM * 1mL in DMSO
¥805.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

顾客使用 Adooq 产品发表的高质量科研文献
Adooq用户使用AG14361 发表的1篇文献
  • Vimal Pandey, .et al. , Scientific Reports, 2019, 9, Article number: 5012 PMID: 30899038
  • 生物活性
    Discription AG14361 is a potent PARP inhibitor, enhanced TMZ cytotoxicity in MMR(mismatch repair)-proficient / deficient cells.
    Targets
    Target Value
    产品信息
    目录号 A10046
    分子式 C19H20N4O
    分子量 320.4
    CAS号 328543-09-5
    SMILES CN(C)CC1=CC=C(C=C1)C2=NC3=CC=CC4=C3N2CCNC4=O
    储存条件

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    溶解性数据
    In vitro (25°C) DMSO 11 mg/mL (34.33 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 4% DMSO+ddH2O 1 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 31.21 mL 156.05 mL 312.11 mL
    0.5 mM 6.24 mL 31.21 mL 62.42 mL
    1 mM 3.12 mL 15.61 mL 31.21 mL
    5 mM 0.62 mL 3.12 mL 6.24 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

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      C2

      V2

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