AGI-5198 (IDH-C35)
目录号: A12902
IDH1 抑制剂
AGI-5198,也被称为 IDH-C35,是一种非常有效且选择性强的突变型 IDH1 抑制剂,已显示出潜在的抗癌活性。
Discription | AGI-5198, also know as IDH-C35, is the a very potent and selective mutant IDH1 inhibitor that was shown to potential anticancer activity. | |||||
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Targets |
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Cell Research |
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目录号 | A12902 |
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分子式 | C27H31FN4O2 |
分子量 | 462.56 |
CAS号 | 1355326-35-0 |
SMILES | CC1=CC=CC=C1C(C(=O)NC2CCCCC2)N(C3=CC(=CC=C3)F)C(=O)CN4C=CN=C4C |
其他名称 | AGI5198,AGI 5198, IDHC35 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 22 mg/mL (47.56 mM) | |
Water | Insoluble | ||
Ethanol | 13 mg/mL (28.1 mM) | ||
In vivo | 0.5% methylcellulose+0.2% Tween 80 | 28 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 21.62 mL | 108.09 mL | 216.19 mL |
0.5 mM | 4.32 mL | 21.62 mL | 43.24 mL |
1 mM | 2.16 mL | 10.81 mL | 21.62 mL |
5 mM | 0.43 mL | 2.16 mL | 4.32 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2