AI-10-49

Name: AI-10-49
SKU: A15521

目录号: A15521

CBFBeta-SMMHC / RUNX1 抑制剂

AI-10-49 Chemical Structure

CAS NO. 1256094-72-0

AI-10-49是一种蛋白质-蛋白质相互作用抑制剂，可选择性结合CBFβ-SMMHC并以0.26 uM的FRET IC50破坏其与RUNX1的结合。

库存：现货

规格	价格	数量
5 mg	￥ 560.00
10 mg	￥ 980.00
25 mg	￥ 1,960.00

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生物活性

AI-10-49是一种蛋白质-蛋白质相互作用抑制剂，可选择性结合CBFβ-SMMHC并以0.26 uM的FRET IC50破坏其与RUNX1的结合。

靶点信息

CBFβ-SMMHC
260 nM

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	15.14 mL	75.7 mL	151.4 mL
0.5 mM	3.03 mL	15.14 mL	30.28 mL
1 mM	1.51 mL	7.57 mL	15.14 mL
5 mM	0.3 mL	1.51 mL	3.03 mL

*The above data is based on the productmolecular weight 660.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A15521
作用机制	Inhibitor (抑制剂)
M. Wt	660.52
Formula	C30H22F6N6O5
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1256094-72-0
SMILES	C1=CC2=C(C=C1OC(F)(F)F)NC(=N2)C3=NC=C(C=C3)OCCOCCOC4=CN=C(C=C4)C5=NC6=C(N5)C=C(C=C6)OC(F)(F)F