Akt

Inhibitory Selectivity

Catalog No.	Inhibitor Name	Akt	Akt1	Akt2	Akt3	Other Targets
A10003	MK-2206 2HCl		***	***	**
A10709	Perifosine	*
A11030	GSK690693		****	***	***	PKCθ,PKCη,PrkX
A11246	Ipatasertib		****	**	***
A11759	AZD5363		****	***	***	ROCK2
A11024	PF-04691502	****				PI3Kδ,PI3Kα,PI3Kγ
A10094	AT7867		**	***	**	PKA,p70 S6K
A13210	Triciribine	*				HIV-1
A11031	CCT128930			****		p70 S6K,PKA
A11034	A-674563		***			PKA,CDK2,GSK-3β
A11032	PHT-427	*				PDK-1
A11286	Akti-1/2		**	*	*
A15809	Uprosertib		*	*	**
A16392	Afuresertib		****	****	****
A12464	AT13148		**	*	**	PKA,ROCK2,ROCK1
A14138	Miltefosine					PI3K,PKC
A10453	Honokiol					MEK
A12720	TIC10 Analogue					ERK
A13460	Deguelin					PI3K
A15903	TIC10					ERK
A11287	A-443654		****
A13590	10-DEBC HCl	*
A16286	ARQ-092 (Miransertib)		****	****	***

Notes:
1.Hover mouse over " * " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " * " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.

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YS-49

Catalog No. A21198
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PI3K/Akt activator

YS-49 is a PI3K/Akt (a downstream target of RhoA) activator, to reduce RhoA/PTEN activation in the 3-methylcholanthrene-treated cells. 了解更多

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SC79

Catalog No. A15541
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Akt phosphorylation activator

SC79是AKT激活剂。SC79绑定到模仿PtdIns（3,4,5）P3的结合的Akt的plecktrin同源（PH）域，以诱导Akt的构象变化，从而增强磷酸化和激活。了解更多

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