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Alcaftadine是H1受体的高亲和力配体，其pKi（8.5）与其他H1抗组胺药相当。Alcaftadine还是H2和H4受体的拮抗剂，对H3受体没有亲和力。
| In vitro | DMSO | 26 mg/mL (84.57 mM) | |
| Water | Insoluble | ||
| Ethanol | 57 mg/mL (185.43 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 32.53 mL | 162.66 mL | 325.32 mL |
| 0.5 mM | 6.51 mL | 32.53 mL | 65.06 mL |
| 1 mM | 3.25 mL | 16.27 mL | 32.53 mL |
| 5 mM | 0.65 mL | 3.25 mL | 6.51 mL |
*The above data is based on the productmolecular weight 307.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A16393 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 307.39 |
| Formula | C19H21N3O |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 147084-10-4 |
| Synonyms | R89674, R 89674, R-89674 |
| SMILES | CN1CC/C(CC1)=C2C3=CC=CC=C3CCN4C(C=O)=CN=C/24 |
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