Alcaftadine
目录号: A16393
H1 histamine receptor 拮抗剂
Alcaftadine 是一种对 H1 受体 具有高亲和力的配体，其 pKi 值（8.5）与其他 H1 抗组胺药 相当。Alcaftadine 还是 H2 和 H4 受体 的拮抗剂，对 H3 受体 没有亲和力。
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生物活性
| Discription | Alcaftadine is a high affinity ligand for the H1 receptor, with a pKi (8.5) that is comparable with that of other H1 antihistamines. Alcaftadine is also an antagonist for H2 and H4 receptors with no affinity for the H3 receptor. |
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产品信息
| 目录号 | A16393 |
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| 分子式 | C19H21N3O |
| 分子量 | 307.39 |
| CAS号 | 147084-10-4 |
| SMILES | CN1CC/C(CC1)=C2C3=CC=CC=C3CCN4C(C=O)=CN=C/24 |
| 其他名称 | R89674, R 89674, R-89674 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 26 mg/mL (84.57 mM) | |
| Water | Insoluble | ||
| Ethanol | 57 mg/mL (185.43 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 32.53 mL | 162.66 mL | 325.32 mL |
| 0.5 mM | 6.51 mL | 32.53 mL | 65.06 mL |
| 1 mM | 3.25 mL | 16.27 mL | 32.53 mL |
| 5 mM | 0.65 mL | 3.25 mL | 6.51 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 147084-10-4 | 147084-10-4 供应商 | 147084-10-4 花费 | 147084-10-4 生产商 | 订购 147084-10-4 | 147084-10-4 代理商