Aldoxorubicin
目录号: A15128
Aldoxorubicin(INNO-206)是多柔比星(DNA拓扑异构酶II抑制剂)的白蛋白结合前药,可在酸性条件下从白蛋白中释放。Aldoxorubicin(INNO-206)在多种癌症细胞系和小鼠肿瘤模型中显示出强大的抗肿瘤活性。
Discription | Aldoxorubicin (INNO-206) is an albumin-binding prodrug of Doxorubicin (DNA topoisomerase II inhibitor), which is released from albumin under acidic conditions. Aldoxorubicin (INNO-206) has potent antitumor activities in various cancer cell lines and in murine tumor models. | ||
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目录号 | A15128 |
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分子式 | C37H42N4O13 |
分子量 | 750.75 |
CAS号 | 1361644-26-9 |
SMILES | [H][C@@]1(O[C@H]2C[C@@](/C(CO)=N/NC(CCCCCN3C(C=CC3=O)=O)=O)(O)CC(C2=C4O)=C(O)C5=C4C(C6=C(OC)C=CC=C6C5=O)=O)O[C@@H](C)[C@@H](O)[C@@H](N)C1 |
其他名称 | INNO-206; DOXO-EMCH |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2