Almorexant HCl

Name: Almorexant HCl
SKU: A14286
Price: 210 CNY
Rating: 5 (1 reviews)

目录号: A14286

OX1/OX2 Ant激动剂

1 篇发表文献

Almorexant HCl 是一种口服活性的双重俄瑞克辛受体拮抗剂，对OX1和OX2受体的IC50分别为6.6 nM和3.4 nM。

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Grouped product items
规格	价格	库存
1mg	¥210.00	现货
5mg	¥595.00	现货
10mg	¥980.00	现货
25mg	¥2,345.00	现货
50mg	¥3,780.00	现货
100mg	¥5,740.00	现货
*10mM 1mL in DMSO**	¥1,015.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Almorexant HCl发表的1篇文献

Ryan J Keenan, .et al. , Br J Pharmacol, 2022, Jul;179(13):3403-3417 PMID: 35112344

生物活性

Discription

Almorexant HCl is an orally active, dual orexin receptor antagonist with IC50 of 6.6 nM and 3.4 nM for OX1 and OX2 receptor 3.

Targets

Target	Value

产品信息

目录号	A14286
分子式	C29H32ClF3N2O3
分子量	549.02
CAS号	913358-93-7
SMILES	CNC(=O)[C@@H](C1=CC=CC=C1)N2CCC3=CC(=C(C=C3[C@@H]2CCC4=CC=C(C=C4)C(F)(F)F)OC)OC.Cl
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	62 mg/mL (112.93 mM)
	Water	Insoluble
	Ethanol	44 mg/mL (80.14 mM)
In vivo	2% DMSO+25% ??-cyclodextrin in saline	8 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.21 mL	91.07 mL	182.14 mL
0.5 mM	3.64 mL	18.21 mL	36.43 mL
1 mM	1.82 mL	9.11 mL	18.21 mL
5 mM	0.36 mL	1.82 mL	3.64 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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