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Almorexant (ACT078573)是一种有效的竞争性双重食欲素1受体(OX1)/orexin 2受体（OX2）拮抗剂，对于OX1和OX2的Ki值分别为1.3和0.17 nM。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.51 mL | 97.55 mL | 195.1 mL |
| 0.5 mM | 3.9 mL | 19.51 mL | 39.02 mL |
| 1 mM | 1.95 mL | 9.75 mL | 19.51 mL |
| 5 mM | 0.39 mL | 1.95 mL | 3.9 mL |
*The above data is based on the productmolecular weight 512.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A12503 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 512.56 |
| Formula | C29H31F3N2O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 871224-64-5 |
| Synonyms | Act-078573 |
| SMILES | CNC(=O)[C@@H](C1=CC=CC=C1)N2CCC3=CC(=C(C=C3[C@@H]2CCC4=CC=C(C=C4)C(F)(F)F)OC)OC |
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