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alpha-Amyloid Precursor Protein Modulator

目录号: A13094
alpha-淀粉样前体蛋白调节剂是一种细胞渗透性的苯并内酯衍生的PKC激活剂(对PKCα的Ki = 11.9 nM),即使在100 nM的浓度下,也能有效增强人类成纤维细胞中淀粉样前体蛋白(APP)的非淀粉样α-加工。
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规格 价格 库存 数量
1mg
¥1,085.00
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2mg
¥1,225.00
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5mg
¥2,415.00
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10mg
¥4,515.00
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25mg
¥8,365.00
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10mM * 1mL in DMSO
¥4,060.00
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生物活性
Discription alpha-Amyloid Precursor Protein Modulator is a cell-permeable benzolactam derived PKC activator (Ki = 11.9 nM for PKCα) that efficiently enhances non-amyloidogenic α-processing of amyloid precursor protein (APP) even at 100 nM in human fibroblas.
Targets
Target Value
产品信息
目录号 A13094
分子式 C27H30F3N3O3
分子量 501.5
CAS号 497259-23-1
SMILES CC(C)[C@H]1C(=O)N[C@@H](CC2=C(N1C)C=CC(=C2)NC(=O)/C=C/C=C/C3=CC=C(C=C3)C(F)(F)F)CO
其他名称 PKC Activator V
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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