Altiratinib (DCC2701)

Name: Altiratinib (DCC2701)
SKU: A14387
Price: 280 CNY
Rating: 5 (288 reviews)

目录号: A14387

c-Met/VEGFR 抑制剂

Altiratinib 是一种新型的 c-MET/TIE-2/VEGFR 抑制剂；在体内有效减少肿瘤负担，并且与体外的 HGF 拮抗剂相比，可以阻断 c-MET pTyr(1349)-介导的信号传导、细胞生长和迁移。

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Grouped product items
规格	价格	库存
5mg	¥280.00	现货
10mg	¥490.00	现货
25mg	¥910.00	现货
50mg	¥1,540.00	现货
100mg	¥2,310.00	现货
*10mM 1mL in DMSO**	¥315.00	现货
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Data Sheet

SDS

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生物活性

Discription

Altiratinib is a novel c-MET/TIE-2/VEGFR inhibitor; effectively reduce tumor burden in vivo and block c-MET pTyr(1349)-mediated signaling, cell growth and migration as compared with a HGF antagonist in vitro.

Targets

Target	Value

产品信息

目录号	A14387
分子式	C26H21F3N4O4
分子量	510.46
CAS号	1345847-93-9
SMILES	FC1=CC=C(NC(C2(C(NC3=C(F)C=C(OC4=CC(/N=C(O)/C5CC5)=NC=C4)C(F)=C3)=O)CC2)=O)C=C1
其他名称	DCC-2701, DCC2701, DCC 2701, DP 5164, DP5164, DP-5164
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	99 mg/mL (193.94 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.59 mL	97.95 mL	195.9 mL
0.5 mM	3.92 mL	19.59 mL	39.18 mL
1 mM	1.96 mL	9.8 mL	19.59 mL
5 mM	0.39 mL	1.96 mL	3.92 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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