AM095 free base
目录号: A14180
LPA1 Receptor 拮抗剂
AM095 是一种新型、高效且具有口服生物利用度的溶血磷脂酸型1受体(LPA1)拮抗剂,其 IC50 值分别针对小鼠或重组人类 LPA1 为 0.73 和 0.98 微米。
Discription | AM095 is a novel, potent and orally bioavailable antagonist of lysophosphatidic acid type 1 receptor (LPA1) with IC50 values of 0.73 and 0.98 μM for mouse or recombinant human LPA1, respectively | |||||
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Cell Research |
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目录号 | A14180 |
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分子式 | C27H24N2O5 |
分子量 | 456.49 |
CAS号 | 1228690-36-5 |
SMILES | CC1=NOC(=C1NC(=O)O[C@H](C)C2=CC=CC=C2)C3=CC=C(C=C3)C4=CC=C(C=C4)CC(=O)O |
其他名称 | AM 095,AM-095 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 84 mg/mL (184.01 mM) | |
Water | Insoluble | ||
Ethanol | 3 mg/mL (6.57 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 21.91 mL | 109.53 mL | 219.06 mL |
0.5 mM | 4.38 mL | 21.91 mL | 43.81 mL |
1 mM | 2.19 mL | 10.95 mL | 21.91 mL |
5 mM | 0.44 mL | 2.19 mL | 4.38 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2