AMD-070 HCl
目录号: A14997
CXCR4 拮抗剂
AMD-070 hydrochloride 是一种强效且选择性的 CXCR4 拮抗剂,在 CXCR4 125I-SDF 抑制结合实验中的 IC50 值为 13 nM,能够抑制 MT-4 细胞和 PBMCs 中 T-细胞型 HIV-1(NL4.3 株)的复制。
Discription | AMD-070 hydrochloride is a potent and selective antagonist of CXCR4 with an IC50 value of 13 nM in a CXCR4 125I-SDF inhibition binding assay, inhibit the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs. |
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目录号 | A14997 |
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分子式 | C21H30Cl3N5 |
分子量 | 458.86 |
CAS号 | 880549-30-4 |
SMILES | NCCCCN(CC1=NC2=CC=CC=C2N1)[C@H]3CCCC4=C3N=CC=C4.[H]Cl.[H]Cl.[H]Cl |
其他名称 | AMD070 hydrochloride, AMD 070 hydrochloride, Mavorixafor HCl |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2