AMG-176
目录号: A18360
MCL-1 inhibitor
AMG-176 是一种效力强大、选择性高且口服生物利用度好的 MCL-1 抑制剂,其 Ki 值为 0.13 nM。
Discription | AMG-176 is a potent, selective and orally bioavailable MCL-1 inhibitor, with a Ki of 0.13 nM. | |||||
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Targets |
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Cell Research |
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目录号 | A18360 |
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分子式 | C33H41ClN2O5S |
分子量 | 613.21 |
CAS号 | 1883727-34-1 |
SMILES | CO[C@H]1\C=C\C[C@H](C)[C@@H](C)S(=O)(=O)NC(=O)c2ccc3OC[C@]4(CCCc5cc(Cl)ccc45)CN(C[C@@H]6CC[C@@H]16)c3c2 |
其他名称 | AMG-176; AMG 176; AMG176; tapotoclax; tapotoclaxum. |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2