AMG 208

Name: AMG 208
SKU: A10063
Price: 175 CNY
Rating: 5 (288 reviews)

目录号: A10063

c-Met 抑制剂

AMG 208 是一种新型的 c-Met 抑制剂，能够抑制 c-Met 的配体依赖性和配体非依赖性激活，从而抑制其酪氨酸激酶活性。

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Grouped product items
规格	价格	库存
2mg	¥175.00	现货
5mg	¥350.00	现货
10mg	¥560.00	现货
25mg	¥1,085.00	现货
50mg	¥1,820.00	现货
100mg	¥2,660.00	现货
200mg	¥3,815.00	现货
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Data Sheet

SDS

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生物活性

Discription

AMG 208 is a novel c-Met inhibitor that inhibits the ligand-dependent and ligand-independent activation of c-Met, inhibiting its tyrosine kinase activity.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10063
分子式	C22H17N5O2
分子量	383.4
CAS号	1002304-34-8
SMILES	COC1=CC2=NC=CC(=C2C=C1)OCC3=NN=C4N3N=C(C=C4)C5=CC=CC=C5
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	0.22 mg/mL (0.57 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	1% DMSO+30% polyethylene glycol+1% Tween 80	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.08 mL	130.41 mL	260.82 mL
0.5 mM	5.22 mL	26.08 mL	52.16 mL
1 mM	2.61 mL	13.04 mL	26.08 mL
5 mM	0.52 mL	2.61 mL	5.22 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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