AMG 337
目录号: A16400
MET 抑制剂
AMG 337 是一种口服的小分子、ATP竞争性、高度选择性的 MET 受体 抑制剂。
Discription | AMG 337 is an oral, small molecule, ATP-competitive, highly selective inhibitor of the MET receptor. | |||||
---|---|---|---|---|---|---|
Cell Research |
|
目录号 | A16400 |
---|---|
分子式 | C23H22FN7O3 |
分子量 | 463.46 |
CAS号 | 1173699-31-4 |
SMILES | CN1N=CC(C2=CN3C([C@@H](C)N4C=CC(N=CC(OCCOC)=C5)=C5C4=O)=NN=C3C(F)=C2)=C1 |
其他名称 | AMG337, AMG-337 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 92 mg/mL (198.5 mM) | |
Water | Insoluble | ||
Ethanol | 92 mg/mL | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 21.58 mL | 107.88 mL | 215.77 mL |
0.5 mM | 4.32 mL | 21.58 mL | 43.15 mL |
1 mM | 2.16 mL | 10.79 mL | 21.58 mL |
5 mM | 0.43 mL | 2.16 mL | 4.32 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2