AMG-47a
目录号: A13167
Lck 抑制剂
AMG-47a 是一种口服生物利用度高的强效抑制剂，针对 Lck 和 T细胞增殖。它在抑制小鼠抗CD3诱导的 IL-2 产生中表现出抗炎活性（ED50 11 mg/kg）。
顾客使用 Adooq 产品发表的高质量科研文献
生物活性
| Discription | AMG-47a is an orally bioavailable potent inhibitor of Lck and T cell proliferation. It exhibits anti-inflammatory activity (ED50 11 mg/kg) in the anti-CD3 induced production of IL-2 in mice. | |||||
|---|---|---|---|---|---|---|
| Cell Research |
|
产品信息
| 目录号 | A13167 |
|---|---|
| 分子式 | C29H28F3N5O2 |
| 分子量 | 535.56 |
| CAS号 | 882663-88-9 |
| SMILES | CC1=C(C=C(C=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)C3=CC4=CN=C(N=C4C=C3)NCCN5CCOCC5 |
| 其他名称 | AMG47a, Geneticin |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 2 mg/mL (3.73 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.67 mL | 93.36 mL | 186.72 mL |
| 0.5 mM | 3.73 mL | 18.67 mL | 37.34 mL |
| 1 mM | 1.87 mL | 9.34 mL | 18.67 mL |
| 5 mM | 0.37 mL | 1.87 mL | 3.73 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
Keywords: 购买 AMG-47a | AMG-47a 供应商 | AMG-47a 花费 | AMG-47a 生产商 | 订购 AMG-47a | AMG-47a 代理商
| 购买 882663-88-9 | 882663-88-9 供应商 | 882663-88-9 花费 | 882663-88-9 生产商 | 订购 882663-88-9 | 882663-88-9 代理商