AMG 548
目录号: A10970
p38 MAPK 抑制剂
AMG 548 是一种强效且选择性的 p38α 抑制剂。它对其他36种激酶具有超过1000倍的选择性,并且能抑制全血LPS刺激的 TNFα。
Discription | AMG 548 is a potent and selective inhibitor of p38α. It displays >1000-fold selectivity against 36 other kinases, and it inhibits whole blood LPS-stimulated TNFα. | ||
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目录号 | A10970 |
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分子式 | C29H27N5O |
分子量 | 461.56 |
CAS号 | 864249-60-5 |
SMILES | O=C1N(C)C(NC[C@H](CC2=CC=CC=C2)N)=NC(C3=CC=NC=C3)=C1C4=CC=C5C(C=CC=C5)=C4 |
其他名称 | AMG-548, AMG548 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2