AMI-1
目录号: A15916
Hmt1p/PRMT1 抑制剂
AMI-1 是一种强效且特异性的组蛋白甲基转移酶（HMT）抑制剂，对酵母 Hmt1p 的 IC50 为 3.0 uM，对人类 PRMT1 的 IC50 为 8.8 uM。
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生物活性
| Discription | AMI-1 is a potent and specific Histone Methyltransferase (HMT) inhibitor with IC50 of 3.0 uM and 8.8 uM for yeast Hmt1p and human PRMT1, respectively. | |||||
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产品信息
| 目录号 | A15916 |
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| 分子式 | C21H14N2Na2O9S2 |
| 分子量 | 548.45 |
| CAS号 | 20324-87-2 |
| SMILES | O=C(NC1=CC2=CC(S(=O)([O-])=O)=CC(O)=C2C=C1)NC3=CC4=CC(S(=O)([O-])=O)=CC(O)=C4C=C3.[Na+].[Na+] |
| 其他名称 | AMI 1, AMI1, AMI-1 disodium salt |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | Warmed: 89 mg/mL (162.27 mM) | |
| Water | 9 mg/mL (16.41 mM) | ||
| Ethanol | Insoluble | ||
| In vivo | PBS | 20 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.23 mL | 91.17 mL | 182.33 mL |
| 0.5 mM | 3.65 mL | 18.23 mL | 36.47 mL |
| 1 mM | 1.82 mL | 9.12 mL | 18.23 mL |
| 5 mM | 0.36 mL | 1.82 mL | 3.65 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 20324-87-2 | 20324-87-2 供应商 | 20324-87-2 花费 | 20324-87-2 生产商 | 订购 20324-87-2 | 20324-87-2 代理商