Anamorelin

Name: Anamorelin
SKU: A12346
Price: 350 CNY
Rating: 5 (1 reviews)

目录号: A12346

GHSR 激动剂

1 篇发表文献

Anamorelin（ONO-7643、RC-1291、ST-1291）是一种口服活性高、亲和力高、选择性的ghrelin受体激动剂，其在HEK293/GRLN FLIPR测定中的EC50值为0.74 nM。Anamorelin目前正在开发中，用于治疗与非小细胞肺癌相关的消瘦/厌食症。

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Grouped product items
规格	价格	库存
5mg	¥350.00	现货
10mg	¥525.00	现货
25mg	¥840.00	现货
50mg	¥1,260.00	现货
100mg	¥2,170.00	现货
200mg	¥3,255.00	现货
*10mM 1mL in DMSO**	¥420.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Anamorelin 发表的1篇文献

Josua Jordi, .et al. , Sci Adv, 2018, Oct; 4(10): eaav1966 PMID: 30402545

生物活性

Discription	Anamorelin (ONO-7643, RC-1291, ST-1291) is an orally active, high-affinity, selective agonist of the ghrelin receptor with an EC50 value of 0.74 nM in the HEK293/GRLN FLIPR assay. Anamorelin is currently under development for the management of non-small lung cancer associated cachexia/anorexia.

产品信息

目录号	A12346
分子式	C31H42N6O3
分子量	546.7
CAS号	249921-19-5
SMILES	CC(C)(C(=O)N[C@H](CC1=CNC2=CC=CC=C21)C(=O)N3CCC[C@](C3)(CC4=CC=CC=C4)C(=O)N(C)N(C)C)N
其他名称	ONO-7643, RC-1291, ST-1291
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	92 mg/mL (168.28 mM)
	Water	Insoluble
	Ethanol	73 mg/mL (133.53 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.29 mL	91.46 mL	182.92 mL
0.5 mM	3.66 mL	18.29 mL	36.58 mL
1 mM	1.83 mL	9.15 mL	18.29 mL
5 mM	0.37 mL	1.83 mL	3.66 mL

Useful Calculator

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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