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￥ 0.00 FLT3
| Catalog No. | Inhibitor Name | FLT3 | Other |
|---|---|---|---|
| A10996 | Cabozantinib | ** | VEGFR2/KDR,c-Met,Kit |
| A10027 | Quizartinib | *** | |
| A11411 | Dovitinib | **** | c-Kit,VEGFR3/FLT4,FGFR1 |
| A10610 | Amuvatinib | * | c-Kit (D816H),PDGFRα (V561D) |
| A10887 | Tandutinib | * | c-Kit,PDGFRβ,CSF-1R |
| A11180 | TG101209 | * | JAK2,RET,JAK3 |
| A10508 | KW-2449 | **** | Abl (T315I),Abl,FGFR1 |
| A10352 | ENMD-2076 | *** | RET,Aurora A,VEGFR3/FLT4 |
| A10198 | Dovitinib Dilactic Acid | **** | c-Kit,FGFR1,VEGFR3/FLT4 |
| A12694 | Pacritinib | ** | JAK2 (V617F),JAK2,TYK2 |
| A12427 | TCS 359 | * | |
| A10352 | ENMD-2076 L-(*)-Tartaric acid | RET,Aurora A,VEGFR3/FLT4 | |
| A15904 | UNC2025 | **** | Mer |
| A14025 | AMG 925 | **** | CDK4,CDK1 |
| A14214 | G-749 | **** | Mer,Aurora B,RET |
| A14156 | AZD2932 | PDGFRβ,VEGFR-2,c-Kit | |
| A10769 | R406 | Syk | |
| A12419 | Go6976 | JAK2,PKCα,PKCβ1 | |
| A11962 | TG-02 (SB1317) | * | CDK2, JAK2 |
| A14411 | Gilteritinib (ASP2215) | **** | Axl |
| A15003 | AST 487 | Ret, c-Kit, KDR, c-Abl | |
| A15520 | Pexidartinib (PLX3397) | * | Kit, CSF-1R |
| A15548 | SU5614 | ||
| A16248 | BPR1J-097 | ** |
Notes:
1.Hover mouse over "" to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of "" is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.
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Gilteritinib (ASP2215)
Catalog No. A14411 FLT3/Axl 抑制剂Gilteritinib (ASP2215)是一种有效的FLT3/AXL抑制剂，对具有AML突变或FLT3-ITD和FLT3-D835的AML具有有效的抗白血病活性。 了解更多
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