Angstrom6 (A6 Peptide)
目录号: A22731
PAI-1 inhibitor
Angstrom6(A6肽)是从单链尿激酶原激活剂(scuPA)衍生的8个氨基酸肽,它干扰了uPA/uPAR级联并消除了下游效应。Angstrom6与CD44结合,从而抑制肿瘤细胞的迁移、侵袭和转移,并调节CD44介导的细胞信号传导。
PAI-1 inhibitor
Discription | Angstrom6 (A6 Peptide) is an 8 amino-acid peptide derived from single-chain urokinase plasminogen activator (scuPA) and interferes with the uPA/uPAR cascade and abrogates downstream effects. Angstrom6 binds to CD44 resulting in the inhibition of migration, invasion, and metastasis of tumor cells, and the modulation of CD44-mediated cell signaling. |
---|
目录号 | A22731 |
---|---|
分子式 | C39H62N10O15 |
分子量 | 910.97 |
CAS号 | 220334-14-5 |
Sequence | Ac-Lys-Pro-Ser-Ser-Pro-Pro-Glu-Glu-NH2 |
Sequence shortening | Ac-KPSSPPEE-NH2 |
其他名称 | A6 Peptide |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2