AOH1160
目录号: A18729
PCNA inhibitor
AOH1160 是一种强效的、首创的、口服小分子增殖细胞核抗原(PCNA)抑制剂,它干扰 DNA 复制,阻断同源重组介导的 DNA 修复,导致细胞周期阻滞并诱导凋亡。
Discription | AOH1160 is a potent, first-in-class, orally available small molecule proliferating cell nuclear antigen (PCNA) inhibitor, interferes with DNA replication, blocks homologous recombination-mediated DNA repair, causes cell-cycle arrest and induces apoptosis. |
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目录号 | A18729 |
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分子式 | C25H20N2O3 |
分子量 | 396.44 |
CAS号 | 2089314-57-6 |
SMILES | O=C(C1=C2C=CC=CC2=CC=C1)NCC(NC3=CC=CC=C3OC4=CC=CC=C4)=O |
其他名称 | AOH 1160, AOH-1160 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2