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AP1189 is a biased agonist at receptors MC1 and MC3. AP1189 reduced cytokine release, an effect reliant on both MC1 and MC3 as evident from the use of Mc1r(-/-) and Mc3r(-/-) macrophages.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 27.9 mL | 139.52 mL | 279.05 mL |
0.5 mM | 5.58 mL | 27.9 mL | 55.81 mL |
1 mM | 2.79 mL | 13.95 mL | 27.9 mL |
5 mM | 0.56 mL | 2.79 mL | 5.58 mL |
*The above data is based on the productmolecular weight 358.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A22488 |
---|---|
M. Wt | 358.36 |
Formula | C16H18N6O4 |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 2 years |
CAS No. | 959850-74-9 |
Synonyms | AP-1189, AP 1189, AP1189, AP1189 acetate, |
SMILES | NC(N/N=C/C=C/C1=CC=CN1C2=CC=CC=C2[N+]([O-])=O)=N.CC(O)=O |
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