Rimiducid (AP1903)

Name: Rimiducid (AP1903)
SKU: A13519
Price: 910 CNY
Rating: 5 (288 reviews)

目录号: A13519

FKBP dimerizer

AP1903 是一种具有亲脂性的他克莫司（tacrolimus）类似物，具有同源二聚化活性。二聚化药物 AP1903 使含有单个酸基替换（Phe36Val）的人类蛋白 FKBP12（Fv）的类似物同源二聚化，使得 AP1903 与野生型 FKBP12 的结合亲和力降低了1000倍。

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Grouped product items
规格	价格	库存
1mg	¥910.00	现货
2mg	¥1,330.00	现货
5mg	¥2,170.00	现货
10mg	¥3,220.00	现货
25mg	¥5,320.00	现货
50mg	¥7,525.00	现货
100mg	¥10,115.00	现货
500mg	¥20,195.00	现货
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Data Sheet

SDS

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生物活性

Discription	AP1903 is a lipid-permeable tacrolimus analogue with homodimerizing activity. Dimerizer drug AP1903 homodimerizes an analogue of human protein FKBP12 (Fv) which contains a single acid substitution (Phe36Val) so that AP1903 binds to wild-type FKBP12 with 1000-fold lower affinity.

产品信息

目录号	A13519
分子式	C78H98N4O20
分子量	1411.63
CAS号	195514-63-7
SMILES	CC[C@@H](C1=CC(=C(C(=C1)OC)OC)OC)C(=O)N2CCCC[C@H]2C(=O)O[C@H](CCC3=CC(=C(C=C3)OC)OC)C4=CC(=CC=C4)OCC(=O)NCCNC(=O)COC5=CC=CC(=C5)[C@@H](CCC6=CC(=C(C=C6)OC)OC)OC(=O)[C@@H]7CCCCN7C(=O)[C@@H](CC)C8=CC(=C(C(=C8)OC)OC)OC
其他名称	AP 1903, AP-1903
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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