Apatinib (YN968D1)

Name: Apatinib (YN968D1)
SKU: A11407
Price: 700 CNY
Rating: 5 (2 reviews)

目录号: A11407

VEGFR 抑制剂

2 篇发表文献

Apatinib（YN968D1）是一种酪氨酸激酶抑制剂，它选择性地抑制血管内皮生长因子受体-2（VEGFR2，也称为KDR），从而抑制VEGF介导的内皮细胞迁移和增殖，阻断肿瘤组织中新血管的形成。

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Grouped product items
规格	价格	库存
5mg	¥700.00	现货
10mg	¥1,050.00	现货
50mg	¥2,450.00	现货
100mg	¥3,150.00	现货
*10mM 1mL in DMSO**	¥770.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Apatinib (YN968D1)发表的2篇文献

Wonjin Park, .et al. , Biomed Pharmacother, 2021, Feb;134:111110 PMID: 33338749

Majid Momeny, .et al. , Sci Rep, 2017, 7: 45954 PMID: 28383032

生物活性

Discription

Apatinib (YN968D1) is a tyrosine kinase inhibitor that selectively inhibits the vascular endothelial growth factor receptor-2 (VEGFR2, also known as KDR) that inhibits VEGF-mediated endothelial cell migration and proliferation thus blocking new blood vessel formation in tumor tissue.

Targets

Target	Value

产品信息

目录号	A11407
分子式	C25H27N5O4S
分子量	493.6
CAS号	811803-05-1
SMILES	CS(=O)(=O)O.C1CCC(C1)(C#N)C2=CC=C(C=C2)NC(=O)C3=C(N=CC=C3)NCC4=CC=NC=C4
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	77 mg/mL (193.72 mM)
	Water	Insoluble
	Ethanol	10 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.26 mL	101.3 mL	202.59 mL
0.5 mM	4.05 mL	20.26 mL	40.52 mL
1 mM	2.03 mL	10.13 mL	20.26 mL
5 mM	0.41 mL	2.03 mL	4.05 mL

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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