Apoptosis Activator 2

Name: Apoptosis Activator 2
SKU: A11944
Price: 175 CNY
Rating: 5 (288 reviews)

目录号: A11944

Apoptosis Activator

Apoptosis Activator 2 强烈诱导 caspase-3 激活、PARP 切割和 DNA 碎片化，这导致细胞的破坏（依赖 Apaf-1）, 其半抑制浓度（IC50）约为 4 微摩尔，对 HMEC、PREC 或 MCF-10A 细胞无效。

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Grouped product items
规格	价格	库存
5mg	¥175.00	现货
10mg	¥315.00	现货
25mg	¥735.00	现货
50mg	¥1,085.00	现货
100mg	¥1,960.00	现货
200mg	¥3,255.00	现货
*10mM 1mL in DMSO**	¥350.00	现货
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Data Sheet

SDS

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生物活性

Discription

Apoptosis Activator 2 strongly induces caspase-3 activation, PARP cleavage, and DNA fragmentation which leads to the destruction of cells (Apaf-1 dependent) with IC50 of ~4 μM, inactive to HMEC, PREC, or MCF-10A cells

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A11944
分子式	C15H9Cl2NO2
分子量	306.1
CAS号	79183-19-0
SMILES	C1=CC=C2C(=C1)C(=O)C(=O)N2CC3=CC(=C(C=C3)Cl)Cl
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	53 mg/mL (173.12 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	32.67 mL	163.35 mL	326.69 mL
0.5 mM	6.53 mL	32.67 mL	65.34 mL
1 mM	3.27 mL	16.33 mL	32.67 mL
5 mM	0.65 mL	3.27 mL	6.53 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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