Apoptozole
目录号: A21177
Hsc70 and Hsp70 抑制剂
Apoptozole（凋亡激活剂 VII）是 Hsc70 和 Hsp70 的 ATPase 领域的抑制剂，其 Kds 分别为 0.21 和 0.14 微摩尔，并且可以诱导凋亡。
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生物活性
| Discription | Apoptozole (Apoptosis Activator VII) is an inhibitor of the ATPase domain of Hsc70 and Hsp70, with Kds of 0.21 and 0.14?μM, respectively, and can induce apoptosis. | ||
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产品信息
| 目录号 | A21177 |
|---|---|
| 分子式 | C33H25F6N3O3 |
| 分子量 | 625.56 |
| CAS号 | 1054543-47-3 |
| SMILES | NC(C(C=C1)=CC=C1CN2C(C3=CC=C(OC)C=C3)=C(C4=CC=C(OC)C=C4)N=C2C5=CC(C(F)(F)F)=CC(C(F)(F)F)=C5)=O |
| 其他名称 | Apoptosis Activator VII |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 96 mg/mL (153.46 mM) | |
| Water | Insoluble | ||
| Ethanol | 24 mg/mL (38.36 mM) | ||
| In vivo | 2% DMSO+30% PEG 300+5% Tween 80+ddH2O | 4 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 15.99 mL | 79.93 mL | 159.86 mL |
| 0.5 mM | 3.2 mL | 15.99 mL | 31.97 mL |
| 1 mM | 1.6 mL | 7.99 mL | 15.99 mL |
| 5 mM | 0.32 mL | 1.6 mL | 3.2 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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