Apremilast (CC 10004)

Name: Apremilast (CC 10004)
SKU: A11289
Price: 245 CNY
Rating: 5 (2 reviews)

目录号: A11289

PDE4 抑制剂

2 篇发表文献

Apremilast，一种新型的PDE4抑制剂，能抑制人类风湿性关节炎滑膜细胞自发产生的肿瘤坏死因子-α，并改善实验性关节炎。

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Grouped product items
规格	价格	库存
5mg	¥245.00	现货
10mg	¥350.00	现货
25mg	¥455.00	现货
50mg	¥420.00	现货
100mg	¥630.00	现货
200mg	¥1,050.00	现货
500mg	¥1,820.00	现货
*10mM 1mL in DMSO**	¥420.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Apremilast (CC 10004)发表的2篇文献

Tomoaki Higuchi, .et al. , Sci Rep, 2023, Nov 8;13(1):19378 PMID: 37938601

Higuchi T, .et al. , Research Square, 2023, Mar 02

生物活性

Discription

Apremilast, a novel PDE4 inhibitor, inhibits spontaneous production of tumour necrosis factor-alpha from human rheumatoid synovial cells and ameliorates experimental arthritis.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A11289
分子式	C22H24N2O7S
分子量	460.5
CAS号	608141-41-9
SMILES	CCOC1=C(C=CC(=C1)[C@@H](CS(=O)(=O)C)N2C(=O)C3=C(C2=O)C(=CC=C3)NC(=O)C)OC
其他名称	CC10004, CC-10004
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	85 mg/mL (184.58 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	0.5% CMC+0.25% Tween 80	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.72 mL	108.58 mL	217.16 mL
0.5 mM	4.34 mL	21.72 mL	43.43 mL
1 mM	2.17 mL	10.86 mL	21.72 mL
5 mM	0.43 mL	2.17 mL	4.34 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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