Aprocitentan

Name: Aprocitentan
SKU: A21999
Price: 315 CNY
Rating: 5 (288 reviews)

目录号: A21999

dual ETA/ETB 拮抗剂

Aprocitentan（ACT-132577）是Macitentan的主要药理活性代谢产物。Aprocitentan是一种双重ETA/ETB拮抗剂，其IC50分别为3.4 nM和987 nM，pA2值分别为6.7和5.5。

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Grouped product items
规格	价格	库存
1mg	¥315.00	现货
5mg	¥770.00	现货
10mg	¥1,190.00	现货
25mg	¥2,240.00	现货
50mg	¥3,185.00	现货
100mg	¥4,795.00	现货
200mg	¥6,475.00	现货
*10mM 1mL in DMSO**	¥980.00	现货
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Data Sheet

SDS

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生物活性

Discription

Aprocitentan (ACT-132577) is the major and pharmacologically active metabolite of Macitentan. Aprocitentan is dual ETA/ETB antagonist with IC50s of 3.4 nM and 987 nM, and pA2 valus of 6.7 and 5.5, respectively.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A21999
分子式	C16H14Br2N6O4S
分子量	546.19
CAS号	1103522-45-7
SMILES	O=S(N)(NC1=NC=NC(OCCOC2=NC=C(Br)C=N2)=C1C3=CC=C(Br)C=C3)=O
其他名称	ACT-132577,ACT132577, ACT 132577
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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