AR-A 014418

Name: AR-A 014418
SKU: A13728
Price: 280 CNY
Rating: 5 (1 reviews)

目录号: A13728

GSK-3 抑制剂

1 篇发表文献

AR-A 014418 是一种选择性的糖原合成酶激酶 3（GSK-3）抑制剂（IC50 = 104 nM）。对 GSK-3 具有特异性，相较于 cdk2 和 cdk5（IC50 值均 > 100 μM）以及其他26种激酶具有更高的选择性。能够抑制β-淀粉样蛋白介导的海马切片中的神经退行性变。

Skip to the end of the images gallery

Skip to the beginning of the images gallery

Grouped product items
规格	价格	库存
5mg	¥280.00	现货
10mg	¥315.00	现货
25mg	¥595.00	现货
50mg	¥1,120.00	现货
100mg	¥1,960.00	现货
200mg	¥2,555.00	现货
*10mM 1mL in DMSO**	¥315.00	现货
更大包装	更多折扣

大包装询价

Notify me when the price drops

全国免运费, 顺丰次日达

重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用AR-A 014418发表的1篇文献

Chia-Hui Huang, .et al. , Toxicol Appl Pharmacol, 2020, Apr 17;397:115013 PMID: 32305283

生物活性

Discription

AR-A 014418 is a selective glycogen synthase kinase 3 (GSK-3) inhibitor (IC50 = 104 nM). Exhibits specificity for GSK-3 over cdk2 and cdk5 (IC50 values are > 100 μM) and over 26 other kinases. Inhibits β-amyloid-mediated neurodegeneration in hippocampal slices.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A13728
分子式	C12H12N4O4S
分子量	308.31
CAS号	487021-52-3
SMILES	COC1=CC=C(C=C1)CNC(=O)NC2=NC=C(S2)[N+](=O)[O-]
其他名称	AR-A014418, ARA 014418, ARA014418
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	55 mg/mL (178.39 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	32.43 mL	162.17 mL	324.35 mL
0.5 mM	6.49 mL	32.43 mL	64.87 mL
1 mM	3.24 mL	16.22 mL	32.43 mL
5 mM	0.65 mL	3.24 mL	6.49 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Keywords: 购买 AR-A 014418 | AR-A 014418 供应商 | AR-A 014418 花费 | AR-A 014418 生产商 | 订购 AR-A 014418 | AR-A 014418 代理商 | 购买 487021-52-3 | 487021-52-3 供应商 | 487021-52-3 花费 | 487021-52-3 生产商 | 订购 487021-52-3 | 487021-52-3 代理商