ARN-3236
目录号: A18725
SIK2 抑制剂
ARN-3236 是一种效力强、口服活性且选择性高的 SIK2 抑制剂。ARN-3236 在 0.8 至 2.6 微摩尔/升的浓度下抑制了 10 种卵巢癌细胞系的生长,IC50 值为此范围。
Discription | ARN-3236 is potent, orally active and selective SIK2 inhibitor. ARN-3236 inhibited the growth of 10 ovarian cancer cell lines at an IC50 of 0.8 to 2.6 μmol/L. | ||
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目录号 | A18725 |
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分子式 | C19H16N2O2S |
分子量 | 336.4 |
CAS号 | 1613710-01-2 |
SMILES | COC1=CC=C(C2=CNC3=NC=CC(C4=CSC=C4)=C32)C(OC)=C1 |
其他名称 | ARN-3236; ARN 3236; ARN3236. |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 62 mg/mL (184.3 mM) | |
Water | Insoluble | ||
Ethanol | 2 mg/mL (5.94 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 29.73 mL | 148.63 mL | 297.27 mL |
0.5 mM | 5.95 mL | 29.73 mL | 59.45 mL |
1 mM | 2.97 mL | 14.86 mL | 29.73 mL |
5 mM | 0.59 mL | 2.97 mL | 5.95 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2