ARQ 531

Name: ARQ 531
SKU: A19823
Price: 245 CNY
Rating: 5 (288 reviews)

目录号: A19823

BTK inhibitor

ARQ 531 是一种可逆的非共价 Bruton's Tyrosine Kinase (BTK) 抑制剂，其 IC50 分别为 0.85 nM 和 0.39 nM，针对 WT-BTK 和 C481S-BTK。

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Grouped product items
规格	价格	库存
2mg	¥245.00	现货
5mg	¥560.00	现货
10mg	¥840.00	现货
25mg	¥1,505.00	现货
50mg	¥2,450.00	现货
100mg	¥3,920.00	现货
*10mM 1mL in DMSO**	¥630.00	现货
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Data Sheet

SDS

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生物活性

Discription	ARQ 531 is a reversible non-covalent inhibitor of Bruton??s Tyrosine Kinase (BTK), with IC50s of 0.85 nM and 0.39 nM for WT-BTK and C481S-BTK, respectively.

产品信息

目录号	A19823
分子式	C25H23ClN4O4
分子量	478.93
CAS号	2095393-15-8
SMILES	O=C(C1=C(C=C(OC2=CC=CC=C2)C=C1)Cl)C3=CNC4=NC=NC(N[C@@H]5CC[C@@H](CO)OC5)=C34
其他名称	ARQ-531, ARQ531
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	86 mg/mL (179.56 mM)
	Water	Insoluble
	Ethanol	6 mg/mL (12.52 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.88 mL	104.4 mL	208.8 mL
0.5 mM	4.18 mL	20.88 mL	41.76 mL
1 mM	2.09 mL	10.44 mL	20.88 mL
5 mM	0.42 mL	2.09 mL	4.18 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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