Arteether
目录号: A17320
Artemotil(β-Arteether)具有抗疟疾活性,用于治疗抗氯喹的恶性疟原虫疟疾,其半抑制浓度(IC50)为1.61 nM。Artemotil 在大鼠、狗和猴子中还表现出中枢神经系统(CNS)神经毒性和厌食毒性。
Discription | Artemotil (β-Arteether) has antimalarial activity for the treatment of chloroquine-resistant Plasmodium falciparum malaria with an IC50 of 1.61 nM. Artemotil also has central nervous system (CNS) neurotoxicity and anorectic toxicity in rats, dogs and monkeys. | |||||
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Cell Research |
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目录号 | A17320 |
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分子式 | C17H28O5 |
分子量 | 312.406 |
CAS号 | 75887-54-6 |
SMILES | C[C@H]1[C@@H](OCC)O[C@@]2([H])[C@]34[C@@]([C@H](C)CC[C@]41[H])([H])CC[C@@](O2)(C)OO3 |
其他名称 | Arteether; Artemotil; beta-Arteether; beta-Dihydroartemisinin ethyl ether; Dihydroartemisinin ethyl ether; NSC 665971; SM 227; |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 59 mg/mL (188.86 mM) | |
Ethanol | <1 mg/mL | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 32.01 mL | 160.05 mL | 320.1 mL |
0.5 mM | 6.4 mL | 32.01 mL | 64.02 mL |
1 mM | 3.2 mL | 16 mL | 32.01 mL |
5 mM | 0.64 mL | 3.2 mL | 6.4 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2