ARV-825

Name: ARV-825
SKU: A16859
Price: 385 CNY
Rating: 5 (288 reviews)

目录号: A16859

BRD4 Inhibitor

ARV-825 是一种异源双功能分子，由一个 BRD4 结合部分和一个 E3 ligase cereblon 结合部分组成，这两部分通过 proteolysis targeting chimera (PROTAC) 技术连接在一起。

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Grouped product items
规格	价格	库存
1mg	¥385.00	现货
5mg	¥980.00	现货
10mg	¥1,190.00	现货
25mg	¥1,855.00	现货
50mg	¥2,555.00	现货
100mg	¥3,850.00	现货
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Data Sheet

SDS

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生物活性

Discription

ARV-825 is a hetero-bifunctional molecule that is composed of a BRD4 binding moiety joined to an E3 ligase cereblon binding moiety using proteolysis targeting chimera (PROTAC) technology.

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A16859
分子式	C46H47ClN8O9S
分子量	923.44
CAS号	1818885-28-7
SMILES	O=C(NC1=CC=C(OCCOCCOCCOCCNC2=CC=CC(C(N3C(CC4)C(NC4=O)=O)=O)=C2C3=O)C=C1)C[C@H]5C6=NN=C(C)N6C7=C(C(C)=C(C)S7)C(C8=CC=C(Cl)C=C8)=N5
其他名称	ARV825, ARV 825
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	97 mg/mL (105.04 mM)
	Water	Insoluble
	Ethanol	3 mg/mL (3.24 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	10.83 mL	54.15 mL	108.29 mL
0.5 mM	2.17 mL	10.83 mL	21.66 mL
1 mM	1.08 mL	5.41 mL	10.83 mL
5 mM	0.22 mL	1.08 mL	2.17 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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