ASP3026
目录号: A11773
ALK 抑制剂
ASP3026 是一种新型且选择性的 ALK 激酶抑制剂。ASP3026 强效地抑制了 ALK 激酶活性,并且在 Tyr-激酶面板中的选择性优于 crizotinib。
Discription | ASP3026 is a novel and selective inhibitor for the ALK kinase. ASP3026 potently inhibited ALK kinase activity and was more selective than crizotinib in a Tyr-kinase panel. | |||||
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Targets |
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Cell Research |
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目录号 | A11773 |
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分子式 | C29H40N8O3S |
分子量 | 580.7 |
CAS号 | 1097917-15-1 |
SMILES | CC(C)S(=O)(=O)C1=CC=CC=C1NC2=NC=NC(=N2)NC3=C(C=C(C=C3)N4CCC(CC4)N5CCN(CC5)C)OC |
其他名称 | ASP 3026, ASP-3026 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 13 mg/mL (22.38 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 17.22 mL | 86.1 mL | 172.21 mL |
0.5 mM | 3.44 mL | 17.22 mL | 34.44 mL |
1 mM | 1.72 mL | 8.61 mL | 17.22 mL |
5 mM | 0.34 mL | 1.72 mL | 3.44 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2