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ASP4132 is an orally active, potent AMPK activator with an EC50 of 18 nM. ASP4132 has anti-cancer activity and makes tumor regression in breast cancer xenograft mouse models.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 10.67 mL | 53.36 mL | 106.72 mL |
| 0.5 mM | 2.13 mL | 10.67 mL | 21.34 mL |
| 1 mM | 1.07 mL | 5.34 mL | 10.67 mL |
| 5 mM | 0.21 mL | 1.07 mL | 2.13 mL |
*The above data is based on the productmolecular weight 937.06. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A22339 |
|---|---|
| M. Wt | 937.06 |
| Formula | C46H51F3N6O8S2 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 2 years |
| CAS No. | 1640294-30-9 |
| Synonyms | ASP-4132,ASP 4132 |
| SMILES | O=C(C1=NC2=CC=C(C3CCN(CC4=CC=C(OC)N=C4)CC3)C=C2N1)N5CCN(CC6=CC=C(C(F)(F)F)C=C6)CC5.O=S(C7=CC=C(C)C=C7)(O)=O.O=S(C8=CC=C(C)C=C8)(O)=O |
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