Tolinapant (ASTX-660)

目录号: A16996
XIAP inhibitor
ASTX660 是一种口服生物利用度高的非肽类拟态拮抗剂,针对 X染色体连锁凋亡抑制蛋白(XIAP)细胞凋亡抑制蛋白1(cIAP1),具有潜在的抗肿瘤和促凋亡活性。1799328-86-1(游离碱)1799328-50-9(盐酸盐)1799328-90-7(甲磺酸盐)1799328-88-3(硫酸盐)
Grouped product items
规格 价格 库存 数量
1mg
¥385.00
现货
2mg
¥665.00
现货
5mg
¥980.00
现货
10mg
¥1,540.00
现货
25mg
¥3,150.00
现货
50mg
¥4,655.00
现货
100mg
¥6,650.00
现货
10mM * 1mL in DMSO
¥1,190.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

顾客使用 Adooq 产品发表的高质量科研文献
生物活性
Discription ASTX660 is an orally bioavailable, non-peptidomimetic antagonist of both X chromosome-linked inhibitor of apoptosis protein (XIAP) and cellular IAP 1 (cIAP1), with potential antineoplastic and pro-apoptoticctivities. 1799328-86-1 (free base) 1799328-50-9 (HCl) 1799328-90-7 (mesylate) 1799328-88-3 (sulfate)
Cell Research
Cell Line Type Value Description References
产品信息
目录号 A16996
分子式 C30H42FN5O3
分子量 539.69
CAS号 1799328-86-1
SMILES OCC1=NC2=C(N(CC2(C)C)C(CN3[C@@H](CN4[C@H](C)COCC4)CN[C@H](C)C3)=O)C=C1CC5=CC=C(F)C=C5
其他名称 ASTX660, ASTX 660
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据
In vitro DMSO 93 mg/mL (172.32 mM)
Water Insoluble
Ethanol 93 mg/mL (172.32 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.53 mL 92.65 mL 185.29 mL
0.5 mM 3.71 mL 18.53 mL 37.06 mL
1 mM 1.85 mL 9.26 mL 18.53 mL
5 mM 0.37 mL 1.85 mL 3.71 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

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    C2

    V2

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