AT-007

Name: AT-007
SKU: A22588
Price: 385 CNY
Rating: 5 (288 reviews)

目录号: A22588

CNS penetrant Aldose Reductase inhibitor

AT-007 是一种口服活性的中枢神经系统（CNS）渗透性醛糖还原酶抑制剂，用于治疗半乳糖血症，其 IC50 值为 100 pM。AT-007 降低有毒的半乳糖醇水平，并防止 GALT 缺乏症大鼠的疾病并发症。

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Grouped product items
规格	价格	库存
1mg	¥385.00	现货
5mg	¥735.00	现货
10mg	¥1,260.00	现货
25mg	¥2,380.00	现货
50mg	¥3,885.00	现货
100mg	¥5,425.00	现货
*10mM 1mL in DMSO**	¥840.00	现货
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Data Sheet

SDS

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生物活性

Discription	AT-007 is an orally active central nervous system (CNS) penetrant Aldose Reductase inhibitor for treatment of Galactosemia with an IC50 value of 100 pM. AT-007 reduces toxic galactitol levels and prevents disease complications in GALT deficiency rats.

产品信息

目录号	A22588
分子式	C17H10F3N3O3S2
分子量	425.4
CAS号	2170729-29-8
SMILES	O=C(O)CC(C1=CSC=C12)=NN(CC3=NC4=CC(C(F)(F)F)=CC=C4S3)C2=O
其他名称	AT007,AT 007
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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