Atabecestat

目录号: A22605
BACE1 inhibitor
Atabecestat (JNJ-54861911) 是一种强效的、能穿透大脑并可口服的 β-位点淀粉样前体蛋白裂解酶1 (BACE1) 抑制剂,能实现强大且高效的脑脊液 Aβ 减少。
Grouped product items
规格 价格 库存 数量
1mg
¥875.00
现货
5mg
¥2,240.00
现货
10mg
¥3,640.00
现货
25mg
¥7,385.00
现货
50mg
¥9,905.00
现货
100mg
¥13,405.00
现货
10mM * 1mL in DMSO
¥2,485.00
现货
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生物活性
Discription Atabecestat (JNJ-54861911) is a potent brain-penetrant and orally active β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor, achieves robust and high CSF Aβ reduction.
产品信息
目录号 A22605
分子式 C18H14FN5OS
分子量 367.4
CAS号 1200493-78-2
SMILES O=C(C1=NC=C(C#N)C=C1)NC2=CC=C(F)C([C@@]3(C)N=C(N)SC=C3)=C2
其他名称 JNJ-54861911, JNJ54861911, JNJ 54861911
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

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    C2

    V2

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