Atabecestat
目录号: A22605
BACE1 inhibitor
Atabecestat (JNJ-54861911) 是一种强效的、能穿透大脑并可口服的 β-位点淀粉样前体蛋白裂解酶1 (BACE1) 抑制剂,能实现强大且高效的脑脊液 Aβ 减少。
Discription | Atabecestat (JNJ-54861911) is a potent brain-penetrant and orally active β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor, achieves robust and high CSF Aβ reduction. |
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目录号 | A22605 |
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分子式 | C18H14FN5OS |
分子量 | 367.4 |
CAS号 | 1200493-78-2 |
SMILES | O=C(C1=NC=C(C#N)C=C1)NC2=CC=C(F)C([C@@]3(C)N=C(N)SC=C3)=C2 |
其他名称 | JNJ-54861911, JNJ54861911, JNJ 54861911 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2