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ATI-2341

目录号: A16351
CXCR4 激动剂
ATI-2341 是一种针对 C-X-C 趋化因子受体 4(CXCR4)的 pepducin(EC50 = 194 nM),它是一种变构激动剂,能激活抑制性异源三聚体 G 蛋白(Gi),以促进抑制 cAMP 产生并诱导钙离子动员。
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规格 价格 库存 数量
1mg
¥665.00
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2mg
¥1,225.00
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5mg
¥2,485.00
现货
10mg
¥4,375.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

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生物活性
Discription ATI-2341, pepducin targeting the C-X-C chemokine receptor type 4 (CXCR4) (EC50 = 194 nM, is an allosteric agonist activating the inhibitory heterotrimeric G protein (Gi) to promote inhibition of cAMP production and induce calcium mobilization.
产品信息
目录号 A16351
分子式 C104H178N26O25S2
分子量 2256.82
CAS号 1337878-62-2
SMILES CCCCCCCCCCCCCCCC(=O)NC(CCSC)C(=O)NCC(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(CCC(=O)N)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CCCNC(=N)N)C(=O)NC(CO)C(=O)NC(CCSC)C(=O)NC(C(C)O)C(=O)NC(CC(=O)O)C(=O)NC(CCCCN)C(=O)NC(CC2=CC=C(C=C2)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(C)C)C(=O)O
其他名称 ATI 2341, ATI2341
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据
In vitro DMSO 85 mg/mL (37.66 mM)
Water Insoluble
Ethanol 2 mg/mL (0.88 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 4.43 mL 22.16 mL 44.31 mL
0.5 mM 0.89 mL 4.43 mL 8.86 mL
1 mM 0.44 mL 2.22 mL 4.43 mL
5 mM 0.09 mL 0.44 mL 0.89 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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