产品详情
Atomoxetine HCl是SLC6A2的一种竞争性特异性抑制剂,同时在大鼠下丘脑突触体中显示出微弱的ST和DAT抑制作用。
靶点信息
Norepinephrine (NE) transporter | 5-HT | DA transporter | ||
5 nM(Ki) | 77 nM(Ki) | 1451 nM(Ki) |
In vitro | DMSO | 51 mg/mL (174.76 mM) | |
Water | 2 mg/mL (6.85 mM) | ||
Ethanol | 33 mg/mL (113.08 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 34.27 mL | 171.34 mL | 342.68 mL |
0.5 mM | 6.85 mL | 34.27 mL | 68.54 mL |
1 mM | 3.43 mL | 17.13 mL | 34.27 mL |
5 mM | 0.69 mL | 3.43 mL | 6.85 mL |
*The above data is based on the productmolecular weight 291.82. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A13424 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 291.82 |
Formula | C17H22ClNO |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 82248-59-7 |
Synonyms | Atomoxetine HCl, LY 139603, LY-139603, Strattera, Tomoxetine hydrochloride |
SMILES | CC1=CC=CC=C1O[C@H](CCNC)C2=CC=CC=C2.Cl |
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